Our new Distinct+ tissue clearing procedure is the one approach that delipidates samples without having transform in morphology and with nominal influence on structural integrity.
Megatome is usually a vibrating microtome meant to part a wide number of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With high blade vibrating frequency and minimized blade deflection, Megatome enables higher-throughput tissue sectioning with uniform surface area profile, as well as small tissue harm and knowledge reduction.
Ask for a quotation or demo Uniformly portion large tissues & sample arrays Megatome is the sole microtome which can segment samples as massive as intact nonhuman primate and human organs, rendering it a must have for fields which include neuropathology.
Megatome is suitable for precision: the blade vibrates at a higher frequency and larger amplitude variety than other microtomes, and incorporates a distinctive deflection Command system.
SE utilizes a rotational electrical field to disperse very electromobile molecules (for instance antibodies or surfactant micelles) throughout a porous sample devoid of damaging electrically charged constructions throughout the tissue. This enables 2-four working day clearing of intact organs,
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Megatome is often a novel microtome that permits for top-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with negligible tissue injury and knowledge reduction.
It’s time and energy to upgrade your microtome to Megatome. With precise higher-frequency slicing for an unmatched number of sample sizes and kinds – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for numerous apps.
The SmartSPIM light sheet microscope delivers unparalleled resolution and acquisition speed in the course of intact tissue volumes, whilst its modular layout permits you to up grade and customize personal factors.
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Defend avoids the variability of hydrogel embedding and the data loss from PFA preservation, guarding specimens for a number of rounds of processing.
Leverage the Apparent+ tissue clearing strategy, as well as megatomi.com eFLASH and patented stochastic electrotransport technologies, to swiftly clear and label whole organs. Crucial highlights and options include:
Our novel Protect tissue preservation system kinds intramolecular bonds employing polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.